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OpenAI Agents SDK, Pydantic-AI, smolagents, Strands, and LangGraph — pick by what your agent needs.
The framework layer is where you actually wire a model to tools and get a working agent loop. Each of the five covered here optimizes for a different shape of the same problem — pick based on what your agent actually needs to do, not by star count.
Quick pick: OpenAI-first production loop → OpenAI Agents SDK; typed outputs and tests → Pydantic-AI; minimal Hugging Face stack → smolagents; AWS-native simplicity → Strands; explicit graphs and branching → LangGraph. See our Python AI SDKs comparison for a longer side-by-side.
